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Sunday, 18 October 2015 15:58

Production of injectable nanocomposite paste in Iran

Production of injectable nanocomposite paste in Iran

Iranian researchers from Materials and Energy Research Center (MERC) succeeded in the production of a type of biocompatible nanocomposite with the ability to carry drugs, which can be injected into damaged bones.

 

After the completion of tests and being mass-produced, the product can be used in orthopedic surgeries to recover and cure bones damaged due to tumors, cysts or fractures.

The use of bone replacement in various forms has increased in recent years. Injectable pastes are samples of the replacements used in tissue engineering. According to the researchers, the aim of the research was to prepare an injectable paste made of bio-glass and sodium alginate polymer with biocompatibility properties.

Injectable pastes should be designed in a way that they can be injected by imposing acceptable force without phase separation between the powder and the liquid. The weak point in the injectable systems is the inconsistency of pastes in contact with physiological liquids in the body, which causes the paste to leave the area before the creation of the bone.

The injected paste can stay in the implant area without moving or being washed by water. Its physical resistance against the diffusion of body liquids and prevention of inconsistency in the structure are among the other advantages of the paste. In addition, the product is able to form hydroxyapatite nanoparticles to create chemical bonds with bone tissue in the body. Results of the research have been published in Journal of the Australian Ceramics Society, vol. 51, issue 2, 2015, pp. 99-108.
EA

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